Posts by: Patricia Inacio PhD

Patricia Inacio PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

May 8, 2018

Fat Accumulation in Brain May Explain Gaucher’s-Parkinson’s Link, Mouse Study Suggests

News

The accumulation of fat molecules in the brain, particularly the molecules that accumulate in Gaucher disease patients, seems to fuel the progression of Parkinson’s disease, a new mouse study suggests. ... Read more

January 18, 2018January 18, 2018

Researchers Identify New Therapeutic Target for Gaucher-Linked Bone Disease

News

Patients with Gaucher disease (GD) frequently develop bone disease, but the mechanisms underlying bone damage remain unknown. New research points to developmental defects and impaired secretion in the cells responsible ... Read more

January 16, 2018

Survey May Help Understand Clinical Features of Gaucher Disease Type 3

News

Using 26 patients gleaned from an international Gaucher disease (GD) registry, researchers have identified common characteristics of Gaucher disease type 3. The long-term follow-up of these patients should help identify treatment ... Read more

December 12, 2017

Cerdelga Seen to Improve Hemoglobin, Platelet Levels in Gaucher Type 1 Adults, Trials Show

News

Treatment with Cerdelga (eliglustat) leads to clinically meaningful long-term improvements in hemoglobin and platelet levels in patients with Gaucher disease type 1 (GD1), data from long-term Phase 2 and Phase ... Read more

October 19, 2017October 19, 2017

New Method of Diagnosing and Monitoring Gaucher Disease Uses Dried Blood Samples

News

Using dried blood samples for measuring the levels of Gaucher disease biomarker glucosylsphingosine is now possible with a newly developed method by a team of researchers at Cincinnati Children’s Hospital ... Read more

August 15, 2017

UK Clinical Trial Aims to Characterize Symptoms and Therapy Response in Gaucher Types 1 and 3

News

An ongoing clinical trial in the United Kingdom aims to determine factors that may predict the severity of Gaucher disease (GD) in adults and children, along with patients’ response to therapy. It focuses particularly on how ... Read more

July 13, 2017July 13, 2017

Imaging Techniques Combo Helps Better Evaluate Bone Disease Risk in Gaucher Patients, Study Finds

News

Researchers found that combining a new, noninvasive technique called trabecular bone score (TBS) with bone mineral density techniques helps to better identify Gaucher disease patients at increased risk for bone fractures. ... Read more

March 7, 2017

Enzyme Replacement Therapy in GD May Affect Immune System Performance, Study Suggests

News

Enzyme replacement therapy (ERT) was associated with decreased levels of inflammatory mediators in a group of patients with Gaucher disease (GD) type 1. The study “Could enzyme replacement therapy promote ... Read more

February 14, 2017

Researchers ID Pre-Symptomatic Early Events in Neurological Forms of Gaucher’s

News

Structural changes, including the abnormal distribution of lysosomes, were detected in neurons of a mouse model of Gaucher disease (GD) and identified as early signs preceding disease symptoms, a study ... Read more

February 2, 2017

Adverse Events in Gaucher Patients Taking Cerdelga Occasional and Not Severe, Study Shows

News

An analysis of four clinical trials testing Cerdelga (eliglustat) for Gaucher disease patients shows the treatment is safe and without serious adverse events. The study, “A pooled analysis of adverse ... Read more